Glutathione 1,500mg

Glutathione 1,500mg (Reduced L-Glutathione)

Glutathione is a naturally occurring tripeptide composed of glutamic acid, cysteine, and glycine, and is widely recognised as one of the body’s most important intracellular antioxidants. Present in nearly all cells, glutathione plays a central role in maintaining redox balance, cellular detoxification processes, and mitochondrial function.

The 1,500mg presentation provides a high-purity form of reduced L-glutathione for laboratory and analytical applications. Due to its involvement in multiple biochemical pathways, glutathione continues to be a key compound in research relating to oxidative stress, cellular resilience, metabolic health, and detoxification mechanisms.

Research Focus and Areas of Interest

1. Oxidative Stress and Redox Balance

Glutathione is central to the regulation of reactive oxygen species (ROS) within cells. Researchers widely study its role in:

• Neutralising free radicals and reactive intermediates

• Supporting glutathione peroxidase (GPx) enzyme activity

• Maintaining the balance between reduced (GSH) and oxidised (GSSG) states

Because oxidative stress is implicated in numerous cellular stress models, glutathione is frequently examined in research exploring cellular ageing, metabolic strain, and mitochondrial efficiency.

2. Detoxification and Phase II Conjugation Pathways

Glutathione is a key component of the body’s Phase II detoxification pathways, particularly in the liver. Research has focused on its ability to:

• Conjugate with xenobiotics via glutathione-S-transferase (GST) enzymes

• Support cellular clearance of environmental and metabolic by-products

• Maintain intracellular defence against electrophilic compounds

These properties make glutathione highly relevant in studies of toxin metabolism, hepatic function, and cellular protection mechanisms.

3. Mitochondrial Function and Energy Metabolism

Mitochondria are particularly vulnerable to oxidative damage due to their role in ATP production. Glutathione is studied for its involvement in:

• Protecting mitochondrial membranes from oxidative stress

• Supporting optimal electron transport chain (ETC) efficiency

• Maintaining redox signalling required for metabolic adaptation

This has positioned glutathione as a central compound in investigations into bioenergetics, fatigue models, and metabolic resilience.

4. Immune Function and Cellular Signalling

Beyond antioxidant activity, glutathione also plays a role in immune regulation and intracellular signalling pathways. Researchers are examining its influence on:

• Lymphocyte activation and proliferation

• Cytokine balance and inflammatory signalling

• Cellular apoptosis and programmed cell survival

Its broad systemic involvement makes glutathione an essential molecule in research related to immune modulation and inflammatory response control.

5. Peptide Stability and Bioavailability Research

As a tripeptide, glutathione exhibits:

• High solubility and intracellular transport capacity

• Rapid turnover in biological systems

• Sensitivity to oxidation, making storage and handling conditions an important factor in research design

Understanding its pharmacokinetics and stability remains an important area of ongoing investigation.

Conclusion

Glutathione 1,500mg represents a high-purity tripeptide central to research in oxidative stress management, detoxification pathways, mitochondrial function, and immune regulation. Due to its widespread involvement in fundamental cellular processes, glutathione remains one of the most extensively studied endogenous peptides in biochemical and molecular biology research.

For research use only. Not approved for human or veterinary applications.

Technical Information

• Synonyms: Reduced L-Glutathione, GSH, γ-L-Glutamyl-L-cysteinylglycine

• Modified Single-Letter Amino Acid Sequence: ECG

• IUPAC Condensed Amino Acid Sequence: γ-Glu-Cys-Gly

• Molecular Weight: 307.32 g/mol

• CAS Number: 70-18-8

• PubChem CID: 124886

• Furhter Referneces: PubChem entry

Stability: Store lyophilised protein at -20°c. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°c for a limited period of time. The lyophilised protein remains stable until expiry date when stored at -20°c. For more information about storage, click here

Source: Biosynthesis

Reconstitution: Reconstitute with Bacteriostatic Water

Usage: Product is prepared for LABORATORY RESEARCH ONLY. Glutathione for sale at Pure Peptides UK is limited to scientific research and education only – Only buy Glutathione if you are a licenced researcher.

* Images for illustration purposes only