Epitalon 10mg

Epitalon – 10 mg

Epitalon (also known as Epithalon or Epithalone) is a synthetic tetrapeptide originally modelled after the active component of bovine pineal gland extract called epithalamin. Designed to activate telomerase while supporting circadian and cellular regulation, Epitalon is provided as a lyophilised powder for research use only. It serves as a highly focused tool for investigating cellular aging mechanisms, epigenetic regulation, antioxidant activity, and mitochondrial function

Research Focus and Areas of Interest

1. Telomerase Activation & Cellular Longevity

Epitalon is widely studied for its ability to activate telomerase in human somatic cells, leading to telomere elongation and extended cellular proliferative potential – making it a powerful tool in aging and longevity research.

2. Genomic Stability & Heterochromatin Dynamics

Research indicates that Epitalon can induce decondensation of heterochromatin in aged lymphocytes and inhibit MMP-9 synthesis in senescent skin fibroblasts, suggesting roles in chromatin regulation and genomic maintenance.

3. Antioxidant & Wound Healing Effects

In cellular models related to diabetic tissue damage, Epitalon demonstrated antioxidant properties, reducing oxidative stress and supporting wound repair mechanisms.

4. Reproductive Cell Integrity & Mitochondrial Protection

Studies report that Epitalon enhances the quality and health of oocytes, cumulus cells, and post-thawed blastocysts, suggesting protective and regenerative potential in reproductive research contexts.

Conclusion

Epitalon is an essential research peptide for exploring molecular aging pathways, especially those involving telomere maintenance, chromatin dynamics, oxidative resilience, and mitochondrial integrity. Supplied strictly for research use only, it is not intended for human or veterinary applications.

Technical Information:

• Synonyms: Epitalon; Epithalon; Epithalone

• Modified Single-Letter Sequence: Ala-Glu-Asp-Gly

• IUPAC Condensed Sequence: Ala-Glu-Asp-Gly

• Molecular Weight: ~390.35 g/mol

• CAS Number: 307297-39-8

• PubChem CID: 219042

• Further References: PubChem Entry

Stability, Source, and Handling

• Stability: Stable for up to 36 months when stored at –20 °C or lower, protected from light and moisture. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°c for a limited period of time. The lyophilised protein remains stable until expiry date when stored at -20°c.

• Source: Synthesised via solid-phase peptide synthesis; supplied with a Certificate of Analysis (COA) confirming purity and identity.

• Reconstitution: Dissolve in sterile water or PBS under aseptic conditions; aliquot and store at –80 °C to preserve integrity. Reconstitute with Bacteriostatic Water

• Usage: Product is prepared for LABORATORY RESEARCH ONLY. Epitalon for sale at Pure Peptides UK is limited to scientific research and education only – Only buy Epitalon if you are a licenced researcher.

* Images for illustration purposes only